It's possible but you will need to add some extra circuitry, a transistor perhaps.
Right now the BUTTON connection (2 left most pins on the TOP header) are: BTN and GND. When these 2 are connected, that is a button "press". The "BTN" signal is a pulled up GPIO high impedance input of the MCU.
I haven't tried it but I think you can do it with an N channel transistor, where you leave the BTN at 5V when 5V is at the gate, and pull down the BTN line when 0V is applied. That way the transistor acts as the button, activated by your 5V "digital button press".
Also don't forget that this will require latching mode, so you need to follow the guide to add the 10K resistor that tells the MCU this is a latching operation (ie not momentary button).